Mycobacterium tuberculosis research paper

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Mycobacterium tuberculosis research paper

One reductant known to drive the Fenton reaction is vitamin C ascorbic acid Vitamin C is an essential nutrient for some mammals and has potent antioxidant properties. The addition of vitamin C to the human diet has led to the elimination of scurvy 12 and some improvement in the treatment of viral and bacterial infections, cardiovascular diseases, cancer, gout, and cataracts 13 — Conflicting reports have suggested either beneficial or no effect of vitamin C in the treatment of TB A few years later, Pichat and Reveilleau demonstrated that vitamin C could sterilize M.

More recently, vitamin C treatment of M. We show that the sterilizing effect of vitamin C on M. Results High doses of vitamin C sterilize M.

Therefore, we first determined that the minimum inhibitory concentration MIC of vitamin C that prevented the growth of M.

Killing kinetic curves were then obtained by treating M. A dose-response relationship was observed and a bactericidal activity was obtained at 2 mM Fig.

Mycobacterium tuberculosis research paper

Strikingly, 4 mM vitamin C sterilized a M. Since vitamin C is rapidly oxidized into dehydroascorbic acid by air, we examined if the limited activity at 1 mM was due to vitamin C degradation. As a result, M.

The killing by vitamin C was not due to acidification of the media since the addition of 4 mM vitamin C to an M. The activity of vitamin C against M. Interestingly, vitamin C activity against M.Latent tuberculosis. Tuberculosis is an infectious disease normally caused by a bacterium called Mycobacterium tuberculosis.

This disease can sometimes generate other infections that may not necessarily present any symptoms but the good news is that only a very small percentage of these infections grow up to the disease level (World Health Organization, ). Tuberculosis is a speciality journal focusing on basic experimental research on tuberculosis, notably on bacteriological, immunological and pathogenesis aspects of the disease.

Mycobacterium tuberculosis research paper

The journal publishes original research and reviews on the host response and immunology of tuberculosis . Tuberculosis is a disease that can take a human being into his grave if not treated on time, this is why the tuberculosis research paper can be a great medium to inform the readers about the disease and aware them how to prevent it.

Jul 17,  · The TB Epidemiologic Studies Consortium (TBESC) was established to strengthen, focus, and coordinate tuberculosis (TB) research.

Feb 27,  · Term Paper on Tuberculosis Tuberculosis Research Paper. TB is an infectious disease that is caused by Mycobacterium tuberculosis usually found in the droplets of an active TB patient (1). According to historical studies, TB was known to the ancient Egyptians, in fact, the analysis of the spinal column of the mummies from BC. Essay Tuberculosis Tuberculosis (TB) is an infectious disease caused by a germ (bacterium) called Mycobacterium tuberculosis. This germ primarily affects the lungs and may infect anyone at any age. In the United States, the number of TB cases steadily decreased until when an increase was noted; TB has continued to rise since. This paper presents an unusual form of disseminated Mycobacterium tuberculosis infection in a dog. The infection lasted at least one year and its main gross lesions were massive cardiac tuberculomas. To the best of our knowledge, this is the first report of heart tuberculomas in a dog.

The TBESC is designed to build the scientific research capacities of state and metropolitan TB control programs, participating laboratories, academic institutions, hospitals, and both non- and for-profit organizations. Tuberculosis (TB) is a contagious and often severe airborne disease caused by infection with Mycobacterium tuberculosis (Mtb) typically affects the lungs, but it also can affect any other organ of the body.

The Mycobacterium tuberculosis complex of organisms consists of other species like, Mycobacterium africanum which is mostly found in the West African countries, Mycobacterium bovis which cause tuberculosis in cattle, Mycobacterium microti, and Mycobacterium avium which causes disease especially prevalent in AIDS patients.

Tuberculosis | NIH: National Institute of Allergy and Infectious Diseases